Sökning: "Liza ljungberg"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Liza ljungberg.

  1. 1. Angiotensin-Converting Enzyme : Effects of Smoking and Other Risk Factors for Cardiovascular Diseases

    Författare :Liza Ljungberg; Karin Persson; Rolf Andersson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cardiovascular diseases (CVDs) are the most common cause of death in Western countries. Smoking, hypertension, diabetes mellitus and hypercholesterolemia are considered as major risk factors. However, the underlying mechanisms by which these factors cause CVDs are not entirely clear. LÄS MER

  2. 2. Angiotensin-converting enzyme in cardiovascular function and dysfunction

    Författare :Liza Ljungberg; Toste Länne; Karin Persson; Urban Alehagen; Thomas Kahan; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Angiotensin-converting enzyme (ACE) is a key enzyme in the renin-angiotensin system, converting angiotensin I to the vasoactive peptide angiotensin II, and degrading bradykinin. Angiotensin II is a multifunctional peptide, acting on a number of different tissues. LÄS MER

  3. 3. Studies of platelet signalling and endothelial cell responses using unique synthetic drugs

    Författare :Caroline Kardeby; Magnus Grenegård; Knut Fälker; Liza Ljungberg; Alastair W. Poole; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemostasis; glycopolymers; purine analogue; PEAR1; GPIbα; CLEC-2; inflammation; ROCK;

    Sammanfattning : Haemostasis is a complex and tightly regulated process which protects us from bleeding. Platelets are essential for maintained haemostasis. Under normal conditions platelets are calmed by antithrombotic substances release by the endothelium. During vascular injury, the platelets will activate and form a haemostatic plug to prevent bleeding. LÄS MER

  4. 4. Impact of Interleukin-6 family cytokine signalling on human endothelial cells and platelets

    Författare :Madelene Lindkvist; Magnus Grenegård; Liza Ljungberg; Alistair W. Poole; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gp130 signalling cytokines; inflammation; transsignalling; JAK STAT; MEK ERK; PI3K AKT; platelet aggregation; vasodilation;

    Sammanfattning : Endothelial cells lining the luminal side of blood vessels creates a barrier between the circulating blood and the extracellular matrix. Endothelial cells have important functions in regulation of vessel tension and inflammation. LÄS MER

  5. 5. Innate immunity in human atherosclerosis and myocardial infarction : Role of CARD8 and NLRP3

    Författare :Geena Paramel Varghese; Karin Fransén; Allan Sirsjö; Liza Ljungberg; Johan Frostegård; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Inflammasome; NLRP3; CARD8; Myocardial infarction; Endothelial cells; Polymorphism; IL-1β; Cytokines; Innate immunity; Biomedicin; Biomedicine;

    Sammanfattning : Atherosclerosis is complex inflammatory disease of the arterial wall with progressive accumulation of lipids and narrowing of the vessel. Increasing evidence suggest that inflammation plays an important role in plaque stability and often accelerate cardiovascular events such as myocardial infarction (MI). LÄS MER