Sökning: "Liselotte Antonsson"

Hittade 1 avhandling innehållade orden Liselotte Antonsson.

  1. 1. Recombinant CXCR4/CCR5 hybrid receptors as tools for studies of HIV-1 receptor usage

    Författare :Liselotte Antonsson; Drug Target Discovery; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; evolution; pathogenesis; cerebrospinal fluid; Medicine human and vertebrates ; TAK-779; RANTES; CXCR4; CCR5; coreceptor; GPCR; HIV-1;

    Sammanfattning : The chemokine receptors CCR5 and CXCR4 are required, together with CD4, for the entry of HIV-1 into target cells. CCR5 using HIV-1 dominates during transmission and the asymptomatic phase of infection. During progression, virus phenotypes with the ability to use CXCR4 emerge in about 50% of infected individuals. LÄS MER