Avancerad sökning

Hittade 1 avhandling som matchar ovanstående sökkriterier.

1. 1. DNA vaccines and bacterial DNA in immunity

   Författare :Lisa Charlotta Bandholtz; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :DNA vaccine; CpG DNA; antimicrobial peptides C. pneumoniae; Shigella spp;

   Sammanfattning : This thesis describes DNA-based vaccination and the importance of bacterial DNA in different immunological perspectives. Intranasal (i.n.) DNA vaccination utilizing a plasmid encoding the chlamydial heat shock protein 60 (p-hsp-60) generated lower bacterial burden and reduced pathology in the lungs of mice after subsequent infection with C. LÄS MER