Sökning: "Lipoproteinlipas"

Hittade 3 avhandlingar innehållade ordet Lipoproteinlipas.

  1. 1. Genetics of type 2 diabetes and the metabolic syndrome

    Författare :Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. LÄS MER

  3. 2. Localization of lipoprotein lipase in mouse pancreas, kidney and placenta : impact of metabolic disturbances on cellular distribution and activity regulation

    Författare :Rakel Nyrén; Gunilla Olivecrona; Paolo Parini; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; pancreas; kidney; placenta; angiopoietin-like protein 4; high-fat diet; obesity; mice; PET CT; nutritional status; triglyceride; GPIHBP1; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Sammanfattning : Lipoprotein lipase (LPL) is the key enzyme for metabolism of triglycerides in plasma lipoproteins. In recent years many new facts about the enzyme and its regulation have been uncovered. The endothelial membrane protein GPIHBP1 translocates LPL through endothelial cells and holds the enzyme in place at the luminal side of the capillary endothelium. LÄS MER

  4. 3. Interaction of Triglyceride-rich Lipoproteins with Platelets and Vitamin K-dependent Coagulation Factors

    Författare :Ning Xu; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglycerides.; Prothrombin; Protein S; Protein C; Platelets; Phospholipids; Metabolism; Lipoproteins; Lipids; Endocytosis; Electron microscopy; Cytochemistry; Coronary heart disease; Blood coagulation factors; Arachidonic acid; Atherosclerosis; Clinical chemistry; Klinisk kemi; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Sammanfattning : 1. During incubation of platelets with 3H-arachidonic acid (20:4, n-6) and 14C-cholesterol doubly labelled and colloidal gold labelled chylomicrons (CMs) and chylomicron remnants (CMRs) CMs were taken up more efficiently than CMRs. Addition of unlabelled CMs, VLDLs, LDLs and HDLs decreased the uptake of labelled CMs. LÄS MER