Sökning: "Linear Odds"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden Linear Odds.

1. 1. Models for Additive and Sufficient Cause Interaction

   Författare :Daniel Berglund; Timo Koski; Helga Westerlind; Ola Hössjer; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Causal Inference; Sufficient Cause; Potential Outcomes; Counterfactual; Additive Interaction; Interaction; MFPO; ICI; Logistic Regression; Linear Odds; Public Health; Interventions; Probabilistic Potential Outcome; Matematisk statistik; Mathematical Statistics;

   Sammanfattning : The aim of this thesis is to develop and explore models in, and related to, the sufficient cause framework, and additive interaction. Additive interaction is closely connected with public health interventions and can be used to make inferences about the sufficient causes in order to find the mechanisms behind an outcome, for instance a disease. LÄS MER

3. 2. The mandibular third molar. Dentists' judgement in the removal of asymptomatic molars

   Författare :Kerstin Knutsson; Lunds universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; visual analogue scale; oral surgery; tooth extraction; third molar; linear models; judgment; Decision making; impacted tooth; Odontology; stomatology; Odontologi;

   Sammanfattning : The aim was to study dentists' judgement on the removal of and on the development of pathology associated with asymptomatic mandibular third molars. Thirty general dental practitioners (GDPs) and 10 oral surgeons were asked to judge 36 molars with equal distribution of three cues: patient's age, angular position and degree of impaction of the molar. LÄS MER

4. 3. Models for Ordered Categorical Pharmacodynamic Data

   Författare :Per-Henrik Zingmark; Mats O Karlsson; E. Niclas Jonsson; France Mentré; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Pharmacodynamic; Modelling; Categorical data; NONMEM; Proportional odds model; Markov model; Differential drug effect model; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

   Sammanfattning : In drug development clinical trials are designed to investigate whether a new treatment is safe and has the desired effect on the disease in the target patient population. Categorical endpoints, for example different ranking scales or grading of adverse events, are commonly used to measure effects in the trials. LÄS MER

5. 4. Statistical methods for twin and sibling designs

   Författare :Johan Zetterqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Twin and sibling studies are valuable in that they allow adjustment for potential confounding factors that are impossible or hard to measure. By measuring associations ‘within-cluster’ it is possible to adjust for many factors that are shared between individuals in the same cluster. LÄS MER

7. 5. Placental molecular mechanisms as pathways linking prenatal exposure to ambient air pollution to preeclampsia and fetal growth

   Författare :Yumjirmaa Mandakh; Avdelningen för arbets- och miljömedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Preeclampsia; Ambient air pollution; placenta; Small-for-gestational age; mitochondrial DNA content; telomere length; global DNA methylation; gene expression; epigenetic age;

   Sammanfattning : Background: Preeclampsia (PE) is a “multifactorial syndrome” in which ambient air pollution may contribute to the etiology of PE. However, the underlying mechanism of this association is not clearly elucidated. LÄS MER