Sökning: "Linda Westermark"

Hittade 1 avhandling innehållade orden Linda Westermark.

  1. 1. Yersinia-phagocyte interactions during early infection

    Författare :Linda Westermark; Maria Fällman; Joan Mecsas; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; dendritic cell; macrophage; neutrophil; T3SS; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. LÄS MER