Sökning: "Lina Thorvaldson"

Hittade 3 avhandlingar innehållade orden Lina Thorvaldson.

  1. 1. The role of cytokines in multiple low dose streptozotocin induced diabetes

    Författare :Lina Thorvaldson; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 2. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus

    Författare :Lina Thorvaldson; Stellan Sandler; Michael Welsh; Maria Holstad; Maria Faresjö; Uppsala universitet; []
    Nyckelord :Cell biology; Cytokine; Diabetes; Tumor necrosis factor-α; Interferon-γ; Interleukin-4; Interleukin-10; Transplantation; Pancreatic islet; Glucose; Regulatory T cell; Cellbiologi;

    Sammanfattning : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. LÄS MER

  4. 3. Immunological strategies for counteracting type 1 diabetes focusing on IL-35 producing regulatory immune cells

    Författare :Zhengkang Luo; Kailash Singh; Stellan Sandler; Per-Ola Carlsson; Martin Blixt; Lina Thorvaldson; Arnaud Zaldumbide; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Regulatory T cell; Regulatory B cell; Interleukin-35; Immunologi; Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Sammanfattning : Type 1 diabetes (T1D) is an autoimmune disease where pancreatic β-cells are attacked by immune cells. Regulatory T (Treg) cells play critical roles in suppressing immune responses and their involvement have been intensively studied in T1D. Low dose IL-2 has been proposed to selectively boost Treg cells in T1D, with only limited success. LÄS MER