Sökning: "Lin28b"

Hittade 3 avhandlingar innehållade ordet Lin28b.

1. 1. Lin28b regulation of early-life B lymphopoiesis. A model system to study how self-reactive B cells develop in early life

   Författare :Hugo Åkerstrand; Avdelningen för molekylär hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lin28b; Developmental Immunology; B-1 B cells; Self-reactivity; B cell development; Early-life;

   Sammanfattning : .... LÄS MER

3. 2. Pediatric Leukemia: Mechanisms of Initiation and Suppression

   Författare :Mohamed Eldeeb; Avdelningen för molekylär hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ETV6-RUNX1; Leukemia Initiation; MLL-rearrangements; Hematopoietic stem cells; LIN28B;

   Sammanfattning : .... LÄS MER

4. 3. Switching ON Fetal B Lymphopoiesis

   Författare :Trine Kristiansen; Avdelningen för molekylär hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B-1 B cells; Lin28; Fetal hematopoietic stem cells;

   Sammanfattning : B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell response. LÄS MER