Sökning: "Likelihood based methods"

Visar resultat 21 - 25 av 237 avhandlingar innehållade orden Likelihood based methods.

1. 21. Development of in silico methods to aid chemical risk assessment : focusing on kinetic interactions in mixtures

   Författare :Elena Golosovskaia; Patrik L. Andersson; Stefan Örn; Patrik Rydén; Ester Papa; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; QSAR; physiologically based kinetic; PBK; zebrafish; ADME; mixture; bisphenols; PFAS; toxicokinetics; environmental science; miljövetenskap; Toxicology; toxikologi;

   Sammanfattning : The environment and biota are constantly exposed to numerous chemicals through contaminated food, soil, water, and air. These chemicals can be taken up and distributed to reach sensitive tissues where they may cause various effects. Many of these chemicals lack data on their environmental and human health effects. LÄS MER

3. 22. Model-Based Hypothesis Testing in Biomedicine : How Systems Biology Can Drive the Growth of Scientific Knowledge

   Författare :Rikard Johansson; Gunnar Cedersund; Tomas Strömberg; Peter Strålfors; Marija Cvijovic; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; systems biology; modeling; ODE; hypothesis testing; falsificationism; insulin signaling; yeast; population heterogeneity; cell-to-cell variation; facilitation; pyramidal; synaptic; bootstrapping; personalized medicine; omics;

   Sammanfattning : The utilization of mathematical tools within biology and medicine has traditionally been less widespread compared to other hard sciences, such as physics and chemistry. However, an increased need for tools such as data processing, bioinformatics, statistics, and mathematical modeling, have emerged due to advancements during the last decades. LÄS MER

4. 23. Secure GNSS-based Positioning and Timing : Distance-Decreasing attacks, fault detection and exclusion, and attack detection with the help of opportunistic signals

   Författare :Kewei Zhang; Panagiotis Papadimitratos; Erik G. Larsson; Christina Pöpper; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electrical Engineering; Elektro- och systemteknik;

   Sammanfattning : With trillions of devices connected in large scale systems in a wired or wireless manner, positioning and synchronization become vital. Global Navigation Satellite System (GNSS) is the first choice to provide global coverage for positioning and synchronization services. LÄS MER

5. 24. A room designed for caring : Experiences from an evidence-based designed intensive care environment

   Författare :Fredrika Sundberg; Maria Henricson; Högskolan i Borås; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care units; critical care; caring; hospital design and construction; evidence-based facility design; built environment; health facility environment; patient rooms; critical illness; patients; family; nurses; Människan i vården; The Human Perspective in Care;

   Sammanfattning : Aim: The overall aim of this doctoral thesis was to examine and evaluate if and how an intensive care unit (ICU) room, which had been designed using the principles of evidence-based design (EBD), impacted the safety, wellbeing and caring for patients, their family members and staff.Methods: Paper I explored the nursing staff experiences of working in an EBD intensive care patient room through 13 interviews that were analysed by qualitative content analysis. LÄS MER

7. 25. Novel likelihood-based inference techniques for sequential data with medical and biological applications

   Författare :Negar Safinianaini; Henrik Boström; Morris Quaid; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : The probabilistic approach is crucial in modern machine learning, as it provides transparency and quantification of uncertainty. This thesis is concerned with the probabilistic building blocks, i.e., probabilistic graphical models (PGM) followed by application of standard deterministic approximate inference, i. LÄS MER