Sökning: "Life-extension"
Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Life-extension.
1. Fatigue life extension in existing steel bridges. High-Frequency Mechanical Impact treatment and Tungsten Inert Gas remelting in life extension and fatigue crack repair of welded steel structures
Sammanfattning : This thesis investigates the performance of improved welds with two post-weld treatment methods for application on existing structures. High-Frequency Mechanical Impact (HFMI) treatment and Tungsten Inert Gas (TIG) remelting were used for fatigue life extension of welded structures. LÄS MER
2. Bifunctional ADAPTs: Opportunity for serological Half-life extension and Targeted therapy
Sammanfattning : Small engineered scaffold proteins (ESPs) gain more and more popularity as biological drugs, due to their specificity and applicability in diagnostics and therapy. Thanks to their high stability, low immunogenicity and low production cost, they present themselves as a promising alternative to the market-leading antibodies. LÄS MER
3. Circular Business Models that Extend Product Value : Going Beyond Recycling to Create New Circular Business Opportunities
Sammanfattning : Over the past ten years, significant industry, policy, and scientific attention has been given to the ‘circular economy’, which aims to create a more sustainable society by decoupling economic growth from resource consumption. Firms are expected to play a significant role in the shift to a circular economy model by implementing circular business models that encourage prolonged use of products, components, and materials. LÄS MER
4. Development of bixin formulations. Extraction, microencapsulation, dispersibility and photostability
Sammanfattning : The aril that covers the seeds of the plant species Bixa orellana is composed of the natural colorants bixin and norbixin, phenolic components and native carbohydrates composed of hemicellulose, starch, and a small fraction of proteins. Bixin is a hydrophobic carotenoid that is water insoluble and is mostly used for coloring oil-based formulations. LÄS MER
5. Rational and Combinatorial Engineering of Affinity Proteins Towards Therapeutical Applications
Sammanfattning : Protein engineering has had an immense impact on the development of biological drugs, including replacement therapies with engineered versions of insulin or factor VIII to treat diabetes or bleeding disorders, and monoclonal antibodies to treat cancer and various other malignancies. Now, with the next generation of treatment modalities coming up, including monoclonal reagents based on alternative scaffolds, gene and cell therapies, the importance of protein engineering to tailor-make these treatments is likely to increase further. LÄS MER