Sökning: "Lewis blood group antigen"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Lewis blood group antigen.
1. Synthesis of oligosaccharides of the Lewis blood group antigen family
Sammanfattning : .... LÄS MER
2. Norovirus, causative agent of winter vomiting disease, exploits several histo-blood group glycans for adhesion
Sammanfattning : Norovirus is recognized as the major cause of outbreaks of gastroenteritis world-wide, yet no vaccines or drugs are available for prevention or treatment of the virus infection. Challenge studies and binding studies using virus-like particles (VLPs) have suggested susceptibility to norovirus infection to be associated with secretor status. LÄS MER
3. Helicobacter pylori adhesion and patho-adaptation : the role of BabA and SabA adhesins in persistent infection and chronic inflammation
Sammanfattning : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. LÄS MER
4. Synthesis of complex carbohydrates corresponding to the Lewis b blood group antigen and Vibrio cholerae polysaccharide structures
Sammanfattning : This thesis is divided into two parts. The first part describes the syntheses of the Lewis b blood group antigen hexasaccharide and parts thereof. The Leb blood group antigen is one of the binding epitopes for the Helicobacter pylori bacteria in the human stomach. LÄS MER
5. Evaluation of fucosylated receptors for Cholera toxin in the human small intestine
Sammanfattning : Cholera toxin (CT) produced by Vibrio cholerae is the causative agent for the diarrheal disease cholera. Cholera is yearly afflicting millions and is estimated to kill over 100 000 people every year. In this thesis I aimed to better understand the role of noncanonical CT receptors, e.g. LÄS MER