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Visar resultat 1 - 5 av 295 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets

    Författare :Gustaf Christoffersson; Mia Phillipson; Kristian Pietras; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; pancreatic islet transplantation; islets of Langerhans; diabetes mellitus; leukocytes; neutrophils; macrophages; pericytes; MMP-9; VEGF-A; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. LÄS MER

  3. 2. Motility of human polymorphonuclear leukocytes : An image processing approach

    Författare :Mikael Gustafsson; Erik Gylfe; Linköpings universitet; []
    Nyckelord :Human polymorphonuclear leukocytes; locomotion; phagocytosis; Saccharomyces cerevisiae; membrane transport; intracellular free calcium; cellular pH; water influx; actin dynamics; digital video microscopy; image processing; fura-2; BCECF; DII; MEDICINE; MEDICIN;

    Sammanfattning : Cell motility is essential for polymorphonuclear leukocyte (PMN) function in the defense against invading microorganisms and in inflammatory processes. Using digital video microscopy and image processing, individual cells were studied during random locomotion, chemotactic locomotion and phagocytosis. LÄS MER

  4. 3. The adenoid defender of the nasopharynx. A study of the cells in the surface secretion in the nasopharynx

    Författare :Magnus Ivarsson; Göteborgs universitet; []
    Nyckelord :Adenoid; nasopharynx; leukocytes; surface secretion; ELISPOT; phagocytosis;

    Sammanfattning : The adenoid is implicated in the pathogenesis of upper airway infections (UAI), but in a not yet understood way. In contrast to the adenoid tissue, the surface secretion on the adenoid, which contains not only pathogenic bacteria and viruses but also leukocytes, has attracted little interest. LÄS MER

  5. 4. DNA methylation in the placenta and in cancerwith special reference to folate transporting genes

    Författare :Sanja Farkas; Torbjörn Nilsson; Lars Breimer; Warren D. Kruger; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA methylation; CRC; placenta; cervix; leukocytes; T-DMRs; folate; array; expression; Biomedicin; Biomedicine;

    Sammanfattning : DNA methylation is an epigenetic mechanism that regulates the gene transcription. Folate is used in cellular synthesis of methyl groups, nucleic acids and amino acids. In complex diseases like cancer and neural tube defects (NTD), various genetic and epigenetic alterations can be found that disrupt the normal cell function. LÄS MER

  7. 5. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury

    Författare :Asad Muhammad; Kirurgi; []
    Nyckelord :Leukocytes; chemokines; platelets; lung; sepsis;

    Sammanfattning : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. LÄS MER