Sökning: "Lepr"

Hittade 5 avhandlingar innehållade ordet Lepr.

1. 1. Molecular mechanisms of antidiabetic effects of estrogen

   Författare :Galyna Bryzgalova; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen; glucose tolerance; insulin sensitivity; lipogenic genes; Lepr; Stat3; G6pc; Srebp1c;

   Sammanfattning : The role of estrogen in the development and regulation of female reproduction is well established. However, recent studies demonstrate that estrogen has a multiple effects on body functions. At present, it is becoming well recognized that one of the important roles of estrogen is the maintenance of glucose homeostasis. LÄS MER

3. 2. Regulation of Leptin by Sexual Maturation and Energy Status in Male Atlantic Salmon (Salmo salar L.) Parr

   Författare :Susanne Trombley; Monika Schmitz; Sylvie Dufour; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Leptin; leptin receptor; Atlantic salmon; Salmo salar; sexual maturation; puberty; energy balance; hepatocytes; sex steriods; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

   Sammanfattning : Leptin is a peripheral adiposity signal and a key hormone in energy balance regulation in mammals, acting as a link between nutritional status and the endocrine reproductive axis. If this is also the role of leptin in fish is not fully understood. LÄS MER

4. 3. The role of leptin in zebrafish (Danio rerio) : Novel insights into appetite regulation and reproduction

   Författare :Emmanouil Tsakoumis; Monika Schmitz; Tatjana Haitina; Åsa Wallén-Mackenzie; Ana Gómez Peris; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; zebrafish; leptin; appetite; GRN; brain; reproduction; oocyte maturation; ovulation; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

   Sammanfattning : The hormone leptin is a peripheral metabolic signal and an important regulator of energy balance. In mammals, leptin acts on the appetite centers in the hypothalamus, causing anorexigenic functions by inhibiting food intake. It is also considered as a link between the nutritional status and the endocrine reproductive axis. LÄS MER

5. 4. Multimodal and multiscale characterization of bone and bone interfaces in health and disease

   Författare :Chiara Micheletti; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osseointegration; characterization; mineralization; ultrastructure; diabetes; osteoporosis; MRONJ; surface functionalization; local drug delivery; titanium; bioactive glass; imaging; spectroscopy; microscale; nanoscale; micro-computed X-ray tomography; micro-Raman spectroscopy; scanning electron microscopy; transmission electron microscopy; PFIB-SEM tomography; electron tomography;

   Sammanfattning : Seeing is believing. Our understanding of phenomena often involves their direct observation. However, bone architecture is challenging to visualize given its multi-level hierarchical organization. LÄS MER

7. 5. Neuromolecular and behavioural profile of teleosts : - effects of boldness, agonistic behaviour and reproductive status

   Författare :Arshi Mustafa; Svante Winberg; Per Erik Olsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histamine receptor 1 hrh1 ; histamine receptor 2 hrh2 ; histamine receptor 3 hrh3 ; boldness; personality; aggression; Histaminergic activity; Serotonergic activty 5-HIAA 5-HT ; Dopaminergic activty DOPAC DA ; spiegeldanio spd ; wild caught zebrafish; AB zebrafish; behaviour; brain.;

   Sammanfattning : This thesis investigates if boldness is reflected in the function of brain histaminergic system in zebrafish (Danio rerio). Moreover, behavioural differences in AB line, spiegeldanio (spd) line and wild caught strain of zebrafish have also been explored apart from the winner-loser effect in AB and spd fish. LÄS MER