Sökning: "Lena Nielsen"
Hittade 5 avhandlingar innehållade orden Lena Nielsen.
1. Förhistorien som kulturellt minne : historiekulturell förändring i svenska läroböcker 1903-2010
Sammanfattning : Scandinavian prehistory has hitherto received little attention in the field of history didactics. In Swedish schools, it is taught in the lower grades in accordance with traditional periodization: the Stone Age, Bronze Age, Iron Age and the Viking Age. LÄS MER
2. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies
Sammanfattning : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. LÄS MER
3. Pharmacometric Evaluation of Biomarkers to Improve Treatment in Oncology
Sammanfattning : Cancer is a family of many different diseases with substantial heterogeneity also within the same cancer type. In the era of personalized medicine, it is desirable to identify an early response to treatment (i.e., a biomarker) that can predict the long-term outcome with respect to both safety and efficacy. LÄS MER
4. Pharmacometrics to characterize innate immune response and antibacterial treatments
Sammanfattning : The immune system protects the host against pathogens by distinguishing self from non-self. However, it is most-often disregarded in pharmacokinetic-pharmacodynamic (PKPD) characterization of (new and old) antibiotics. LÄS MER
5. Quantifying effects of antimicrobial drug combinations by modelling and simulation
Sammanfattning : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. LÄS MER