Sökning: "Lena Lilja"

Hittade 1 avhandling innehållade orden Lena Lilja.

1. 1. Molecular mechanisms regulating exocytosis : studies of insulin secretion and neurotransmitter release

   Författare :Lena Lilja; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cdk5; cell line; DARPP-32; dephosphorylation; exocytosis; inhibitor-1; insulin; islet; kinase; munc18; myotube; p35; p39; phosphatase; phosphorylation; PP1; presynaptic mechanisms; secretion; subcellular localization.;

   Sammanfattning : In order to achieve normal physiology the secretion of hormones and neurotransmitters needs to be firmly controlled. The basic molecular machinery mediating regulated exocytosis of hormones and neurotransmitters is in principal revealed, but knowledge about how the individual components are spatially and temporarily coordinated is limited. LÄS MER