Sökning: "Leishmania major"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Leishmania major.
1. Leishmania donovani Lipophosphoglycan : Modulation of Macrophage and Dendritic Cell Function
Sammanfattning : Leishmania donovani is a blood-borne tropicial parasite, which infects humans through bites by Phlebotomus sandflies. The parasite survives and multiplies inside macrophages in inner organs, and causes the deadly disease visceral leishmaniasis (Kala-Azar). LÄS MER
2. Leishmania and HIV-1 interaction : immunopathogenic mechanisms
Sammanfattning : Both Leishmania and HIV can infect and multiply in macrophages, and both can dysregulate the T-helper (Th) immune system. This thesis was, therefore, undertaken to unravel some of the underlying immunopathogenic mechanisms of the interaction of the two pathogens. LÄS MER
3. Innate and acquired immunity to Leishmania in humans : the role of the host versus the parasite
Sammanfattning : Leishmania are intracellular protozoan parasites of macrophages which induce chronic diseases in man. The study of this parasite has been instrumental in elucidating many facets of the immune system. Our study set out to understand the immune regulatory mechanisms involved in resistance and susceptibility. LÄS MER
4. The contribution of epidermal apoptosis to the clinical outcome of Leishmania aethiopica induced cutaneous Leishmaniasis, and its laboratory diagnosis using low cost culture media
Sammanfattning : Background: Cutaneous Leishmaniasis (CL) induced by Leishmania aethiopica has two clinical manifestations: ulcerating, self-healing CL and non-ulcerating, non-healing CL. The grossly disfiguring multiple nodules on the face and exterior surface of limbs during non-ulcerative CL are sometimes misdiagnosed as other skin infections. LÄS MER
5. Neuroimmune interaction in cutaneous leishmaniasis
Sammanfattning : This study was conducted to ascertain how complex interactions between the immune and nervous systems are involved in the pathophysiology of cutaneous leishmaniasis (CL) caused by Leishmania (L.) major. LÄS MER