Sökning: "Leif A Kirsebom"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Leif A Kirsebom.

  1. 1. Mutations in ribosomal protein L7/L12 : structural and functional studies

    Författare :Leif A. Kirsebom; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  3. 2. tRNA Gene Structures in Bacteria

    Författare :B. M. Fredrik Pettersson; Leif A. Kirsebom; Anders Byström; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; mikrobiologi; Microbiology;

    Sammanfattning : In bacteria, tRNA molecules are produced as precursors with additional nucleotides both upstream and downstream of the tRNA coding sequence. To generate a mature tRNA, the endoribonuclease RNase P removes the upstream sequence, while a number of enzymes can remove the downstream sequence. LÄS MER

  4. 3. Distal to Proximal—Functional Coupling in RNase P RNA-mediated Catalysis

    Författare :Shiying Wu; Leif A. Kirsebom; Britt-Marie Sjöber; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribozyme; RNase P; Induced fit model; tRNA progressing; Substrate interaction;

    Sammanfattning : RNase P is a ubiquitous ribonuclease responsible for removing the 5’ leader of tRNA precursor. Bacterial RNase P contains one RNA (RPR) and one protein (RPP) subunit. However, the number of protein variants depends on the origin. The RNA subunit is the catalytic subunit that in vitro cleaves its substrate with and without the protein subunit. LÄS MER

  5. 4. Dynamic Organization of Molecular Machines in Bacteria

    Författare :Bhupender Singh; Santanu Dasgupta; Leif A. Kirsebom; Don G. Ennis; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molecular machines; bacteria; cell cycle; ribosome; replisome; divisome; spore; E. coli; H. pylori; Mycobacteria; Microbiology; Mikrobiologi; Mikrobiologi; Microbiology;

    Sammanfattning : Bacterial cells were once treated as membrane-enclosed bags of cytoplasm: a homogeneous, undifferentiated suspension in which polymers (proteins, nucleic acids, etc.) and small molecules diffused freely to interact with each other. LÄS MER

  7. 5. Morphological changes in mycobacteria

    Författare :Malavika Ramesh; Leif A. Kirsebom; Anders Løbner-Olesen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacteria; pleomorphism; dnaK_3; microaerobic condition; Morphology; oxygen deprivation; spore-like cells; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Morphological variations at different stages and conditions of growth has been observed frequently in various mycobacteria. Despite years of research, the molecular basis of such variations is still not clear and requires further elucidation. LÄS MER