Sökning: "Legionella pneumophila"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Legionella pneumophila.

  1. 1. Evolution and host-specific adaptations of Legionella pneumophila

    Författare :Anaísa B. Moreno; Lionel Guy; Dan I. Andersson; Fredrik Söderbom; Alexander W. Ensminger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Evolution; Legionella pneumophila; host-adaptation; experimental evolution; Acanthamoeba castellanii; transfection; Mikrobiologi; Microbiology;

    Sammanfattning : How bacteria evolve pathogenic traits is shaped by their communities and environments. Legionella pneumophila is ubiquitous in aquatic habitats, where it persists by replicating within a broad range of protozoan hosts. Using the same mechanisms, L. LÄS MER

  2. 2. Synthesis and investigation of bacterial effector molecules

    Författare :Michael Franz Albers; Christian Hedberg; Christian Hackenberger; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial effectors; organic synthesis; Legionella; PTM; peptide synthesis; nucleotide chemistry; Biorganic Chemistry; bioorganisk kemi;

    Sammanfattning : During infections, bacterial microorganisms initiate profound interactions with mammalian host cells. Usually defense mechanisms of the host destroy intruding bacteria in rapid manner. However, many bacterial pathogens have evolved in a way to avoid these mechanisms. LÄS MER

  3. 3. Studies on cell wall recycling and modification in Gram-negative bacteria

    Författare :Michael C. Gilmore; Felipe Cava; Peter A Lind; Teresa Frisan; Jean-François Collet; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Peptidoglycan recycling; bacterial cell wall; antibiotics; Agrobacterium tumefaciens; Escherichia coli; Legionella pneumophila; mikrobiologi; Microbiology; Biochemistry; biokemi;

    Sammanfattning : The bacterial cell wall is made from peptidoglycan (PG), a heteropolymer which forms a bag-like exoskeleton that envelopes the cell. PG is constantly remodelled during growth and division, and in response to environmental stimuli. LÄS MER

  4. 4. Detection and epidemiologic subtyping of Legionella pneumophilia using DNA-based molecular methods

    Författare :Sverker Bernander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Legionella; AFLP; PFGE; Nested PCR; lag-1; hospital; outbreaks;

    Sammanfattning : Legionella pneumophila causes 2 - 6 % of hospitalised pneumonia cases. Several community- and hospital-acquired outbreaks have been reported over the years. Legionnaires' disease (LD) or legionellosis is also a frequent cause of pneumonia amongst travellers. LÄS MER

  5. 5. Selective protein functionalisation via enzymatic phosphocholination

    Författare :Philipp Ochtrop; Christian Hedberg; Tom Grossmann; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemical biology; organic synthesis; site-selective protein labeling; PTM; phosphocholination; nucleotides; bioorthogonal chemistry; proteomics; IMPDH2;

    Sammanfattning : Proteins are the most abundant biomolecules within a cell and are involved in all biochemical cellular processes ultimately determining cellular function. Therefore, to develop a complete understanding of cellular processes, obtaining knowledge about protein function and interaction at a molecular level is critical. LÄS MER