Sökning: "Laura Rusche"

Hittade 1 avhandling innehållade orden Laura Rusche.

1. 1. Mating type switching and transcriptional silencing in Kluyveromyces lactis

   Författare :Emad Barsoum; Åström Stefan; Laura Rusche; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mating type switch; transcriptional silencing; alpha3; transposase; Ume6; Mts1; Ras; cAMP; K. lactis; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

   Sammanfattning : To explore the similarities and differences of regulatory circuits among budding yeasts, we characterized the role of unscheduled meiotic gene expression 6 (UME6) and a novel mating type switching pathway in Kluyveromyces lactis. We found that Ume6 was required for transcriptional silencing of the cryptic mating-type loci HMLα and HMRa. LÄS MER