Sökning: "Laura Mesas Sánchez"

Hittade 1 avhandling innehållade orden Laura Mesas Sánchez.

  1. 1. Organocatalytic Acylation for the Kinetic Resolution of Secondary Aryl Alcohols Synthetic Applications and Mechanistic Studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Laura Mesas Sánchez; Uppsala universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; kinetic resolution; organocatalysis; secondary alcohols; reaction progress kinetic analysis; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Sammanfattning : The research described in this thesis focuses on the catalytic acylative kinetic resolution (KR) of aromatic secondary alcohols, using a planar-chiral 4-(dimethylamino)pyridine (DMAP) organocatalyst.In the first part of this thesis, the substrate scope of the above mentioned process was expanded to aromatic secondary alcohols that contain an extra functional group in the alkyl moiety, such as 1,2-azido alcohols, 2-hydroxy-2-aryl-ethylphosphonates and 2-hydroxy-2-aryl esters. LÄS MER