Sökning: "Lars-Owe D Koskinen"

Hittade 5 avhandlingar innehållade orden Lars-Owe D Koskinen.

1. 1. On evolution of intracranial changes after severe traumatic brain injury and its impact on clinical outcome

   Författare :Lukas Bobinski; Lars-Owe Koskinen; Magnus Olivecrona; Peter Lindvall; Marklund Niklas; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe traumatic brain injury; ICP targeted therapy; ICP; decompressive craniectomy; S100B; NSE; cranioplasty; neurokirurgi; Neurosurgery;

   Sammanfattning : Severe traumatic brain injury (sTBI) is a cause of death and disability worldwide and requires treatment at specialized neuro-intensive care units (NICU) with a multimodal monitoring approach. The CT scan imaging supports the monitoring and diagnostics. The level of S100B and neuron specific enolase (NSE) reflects the severity of the injury. LÄS MER

3. 2. Effects of TRH, naloxone and morphine on cerebral and some other peripheral blood flows : evidence for a physiological role of TRH in cardiovascular control

   Författare :Lars-Owe D. Koskinen; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

4. 3. Biomarkers for diagnosis and prognosis in amyotrophic lateral sclerosis

   Författare :Arvin Behzadi; Karin Forsberg; Anton E. Tjust; Anna Wuolikainen; Per Zetterström; Lars-Owe D. Koskinen; Andreas Puschmann; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyotrophic lateral sclerosis; biomarkers; neurofilaments; cytokines; troponin; cystatin C; Neurology; neurologi;

   Sammanfattning : Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of upper and lower motor neurons, leading to paresis, muscle atrophy, and respiratory failure. ALS can be difficult to diagnose and prognosticate early. LÄS MER

5. 4. Population-based studies of higher-level gait disorders and hydrocephalus : focused on brain ventricular morphometry and patient outcomes following shunt surgery

   Författare :Jenny Larsson; Jan Malm; Anders Eklund; Hanna Israelsson Larsen; Lars-Owe D. Koskinen; Uwe Kehler; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Higher-level gait disorder; Idiopathic Normal Pressure Hydrocephalus; Ventriculomegaly; Falls; Fear of Falling; Self-efficacy; Depression; Quality of life; Adverse events; Headache; Epilepsy; Abdominal pain;

   Sammanfattning : Background: To study gait is of great importance for the health of the aging population. Higher-level gait disorders (HLGD) are characterized by a slow, symmetrical, unsteady gait. Its cause is most often unknown. HLGD in combination with ventriculomegaly (i. LÄS MER

7. 5. On severe traumatic brain injury : aspects of an intra cranial pressure-targeted therapy based on the Lund concept

   Författare :Magnus Olivecrona; Lars-Owe D Koskinen; Bertil Romner; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; severe traumatic brain injury; ICP targeted therapy; ICP; hemicraniectomy; seizures; prostacyclin; microdialysis; outcome; S100B; NSE; Neurosurgery; Neurokirurgi;

   Sammanfattning : Severe Traumatic Brain Injury (sTBI) is a major cause of mortality and morbidity. At the Department of Neurosurgery Umeå University Hospital subjects with sTBI are treated with an intracranial pressure (ICP) guided therapy based on physiological principles, aiming to optimise the microcirculation of the brain so avoiding secondary brain injuries. LÄS MER