Sökning: "Lars Wennberg"

Hittade 2 avhandlingar innehållade orden Lars Wennberg.

1. 1. Islet xenograft rejection : studies in the pig-to-rodents and pig-to-primate models

   Författare :Lars Wennberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Xenotransplantation; islets; rejection; porcine; immunosuppression; C-peptide;

   Sammanfattning : The aims of this thesis was: 1) to compare islet allo- and xenograft rejection in rats, using immunosuppression with CsA in a mixed allogeneic-xenogeneic islet transplantation model, 2) to evaluate the efficacy of various immunosuppressive drugs, with special reference to Leflunomide, in preventing islet xenograft rejection in the pig-to-rat model, 3) to perform an immunohistochemical study of porcine islet xenograft rejection in primates including primates treated with CsA+DSG, and 4) to study the metabolism and excretion of porcine C-peptide in mice, with special reference to the use of donor-specific C-peptide for monitoring islet xenograft function. In summary, the results were as follows: 1. LÄS MER

3. 2. Aspects of priapulid development

   Författare :Sofia A Wennberg; Graham Budd; Lars Holmer; Ralf Janssen; Prpic Nikola; Uppsala universitet; []
   Nyckelord :Earth sciences; Priapulus caudatus; Priapulida; Ecdysozoa; larval development; embryology; Geovetenskap;

   Sammanfattning : The phylum Priapulida is a small group of marine worms that is allied with the nematodes, kinorhynchs, loriciferans and nematomorphs in a clade called the Cycloneuralia or Introverta. Together with the arthropods they are generally considered to comprise the Ecdysozoa, a clade of moulting animals. LÄS MER