Sökning: "Lars Thelander"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Lars Thelander.

  1. 1. The p97 ATPase and the Drosophila Proteasome : Protein Unfolding and Regulation

    Författare :Kristian Björk Grimberg; Patrick Young; Neus Visa; Lars Thelander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteasome; ubiquitin; p97; unfolding; regulation; RNAi screen; high-throughput screen; cnc; basic leucine zipper; transcription factors; proteasome inhibition; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : For all living systems, there is a requirement to recycle and regulate proteins. In eukaryotic organisms this is accomplished by the proteasome. The p97 ATPase is another highly conserved and essential complex present throughout the eukaryotic cell. LÄS MER

  3. 2. Syntax som social resurs : En studie av samkonstruktionssekvensers form och funktion i svenska samtal

    Författare :Gustav Bockgård; Mats Thelander; Per Linell; Jan Anward; Lars-Gunnar Andersson; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Swedish language; joint production; co-construction; anticipatory completion; appendor question; interactional linguistics; conversation analysis; grammar; constructional schema; interaction; Swedish; Svenska; Swedish language; Svenska språket;

    Sammanfattning : One prerequisite in order for conversation to take place is cooperation between the participants. In other words, each person must adjust his or her behavior according to the actions of the other participants. One method that the speakers use in interaction is the co-construction of syntactic units. LÄS MER

  4. 3. Regulation of the Expression of Mouse Ribonucleotide Reductase Small Subunit at the Levels of Transcription and Protein Degradation

    Författare :Anna Lena Chabes; Lars Thelander; Ylva Engström; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; ribonucleotide reductase; transcription; protein degradation; cell cycle; Molekylärbiologi; Molecular biology; Molekylärbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Deoxyribonucleic acid (DNA) carries all the genetic information of a cell. Ribonucleotide reductase (RNR) provides balanced pools of all four dNTPs, the building blocks of DNA. These building blocks are needed during DNA synthesis and repair. LÄS MER

  5. 4. Transcriptional regulation of mouse ribonucleotide reductase

    Författare :Anna Elfving; Lars Thelander; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ribonucleotide reductase; promoters; cell cycle; transcriptional regulation; primer extension; protein purification; EMSA; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : All living organisms are made of cells and they store their hereditary information in the form of double stranded DNA. In all organisms DNA replication and repair is essential for cell division and cell survival. These processes require deoxyribonucleotides (dNTPs), the building blocks of DNA. LÄS MER

  7. 5. Salvage and de novo synthesis of nucleotides in Trypanosoma brucei and mammalian cells

    Författare :Artur Fijolek; Lars Thelander; Arne Holmgren; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nucleotides; ribonucleotide reductase; Ara-A; p53R2; Trypanosoma brucei; African sleeping sickness; trypanosomiasis; CTP synthetase; adenosine kinase; acivicin; adenine arabinoside; Biochemistry; Biokemi;

    Sammanfattning : All living cells are dependent on nucleic acids for their survival. The genetic information stored in DNA is translated into functional proteins via a messenger molecule, the ribonucleic acid (RNA). Since DNA and RNA can be considered as polymers of nucleotides (NTPs), balanced pools of NTPs are crucial to nucleic acid synthesis and repair. LÄS MER