Sökning: "Lars Johannesen"

Hittade 2 avhandlingar innehållade orden Lars Johannesen.

1. 1. Improving assessment of cardiovascular arrhythmic safety of new pharmacologic agents

   Författare :Lars Johannesen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Fourteen drugs have been removed from the market worldwide due to an increased risk of torsade de pointes (TdP), a potentially fatal ventricular arrhythmia. Almost all of the removed drugs that have been linked to an increased risk for TdP have been shown to block the human ether-à-go-go-related gene (hERG) potassium channel. LÄS MER

3. 2. The value of evaluating and implementing pharmaceuticals

   Författare :Kasper Johannesen; Martin Henriksson; Lars-Åke Levin; Magnus Janzon; Katarina Steen Carlsson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Pharmaceuticals are a central part of high-quality health care and a resource for improving population health. However, high prices set by private companies who develop and own the rights to new pharmaceuticals question the value that they contribute to the health care system. LÄS MER