Sökning: "Lars Egevad"

Hittade 2 avhandlingar innehållade orden Lars Egevad.

  1. 1. Heterogeneity and biopsy strategies in prostate cancer

    Författare :Lars Egevad; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Prostate cancer; core biopsy; tumor. volume; computer simulation; DNA ploidy; tumor heterogeneity; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : For the diagnosis of prostate cancer, there is a need to develop biopsy strategies, that give representative information both for detection of cancer and for assessment of prognostic indicators.In 80 men, transrectal core biopsies from 10 standardized positions were taken before radical prostatectomy. LÄS MER

  2. 2. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Författare :Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Nyckelord :urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER