Sökning: "Large scale fermentations"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Large scale fermentations.

  1. 1. Large-scale Bioreactor Phenomena and Characteristics; Effects on E.coli fed batch fermentations on 30m3 scale

    Författare :Gustav Silfversparre; KTH; []
    Nyckelord :Large-scale; E.coli; fed batch; concentration gradients; mixing;

    Sammanfattning : Due to economical and practical limitations the fluiddynamics and mass transport properties are less optimal inlarge-scale bioreactors compared to lab-scale bioreactors. Incombination with the microbial reaction rates this creates amuch more dynamic environment for cells cultivated inlarge-scale bioreactors compared to lab-scale bioreactors. LÄS MER

  3. 2. Probing Control : Analysis and Design with Application to Fed-Batch Bioreactors

    Författare :Stéphane Velut; Institutionen för reglerteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Elektronik och elektroteknik; Electronics and Electrical technology; Large scale fermentations; Extremum control; Feeding strategy; Probing control; Fed-batch bioreactors; Automation; robotics; control engineering; Automatiska system; robotteknik; reglerteknik;

    Sammanfattning : In most control problems the objective is to control the output at a desired value in spite of disturbances. In some cases, the best setpoint is not known a priori and it should be found online to optimize the process performance. This thesis examines a probing strategy that can be applied for this class of problems. LÄS MER

  4. 3. Multivariate monitoring, modelling and control for stabilization of bioprocesses

    Författare :Christian Cimander; Gunnar Lidén; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : The obstacles to overcome low reproducibility and stability of bioprocesses are numerous. Underlying biochemical processes are inherently non-linear, complex and subject to shifting initial conditions. Problems with high variability are also associated to production strains and scale-up of a bioprocess to largescale bioreactors. LÄS MER

  5. 4. An analytical framework for studying transcriptional regulation

    Författare :Christoph Sebastian Börlin; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcription factor; ChIP-exo; S. cerevisiae; transcriptional regulation;

    Sammanfattning : The state and behavior of any living cell is controlled by a complex interplay of different regulatory processes, with the regulation of transcription playing a major role. When a cell adapts to a new environment it often does that by modulating gene transcript levels, mainly through changes in transcription factor binding events. LÄS MER

  7. 5. Carbon metabolism in non-conventional yeasts: biodiversity, origins of aerobic fermentation and industrial applications

    Författare :Nerve Zhou; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aerobic fermentation; carbon metabolism; non-conventional yeasts; strain development;

    Sammanfattning : Abstract: For millennia, the “yeast” Saccharomyces cerevisiae remains by far the most extensively studied and exploited yeast in food and industrial applications. A number of researches and developments have been done since the establishment of the biochemical function of yeast by Louis Pasteur in 1860, however modern lifestyles often connected to food related health trends demand new and innovative food products. LÄS MER