Sökning: "Laminin"

Visar resultat 11 - 15 av 105 avhandlingar innehållade ordet Laminin.

  1. 11. Gene expression studies of pregastrulation development: the basement membrane is essential for cell differentiation

    Författare :Mikael Åkerlund; Muskelbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscular dystrophy; development; Basement membrane; laminin; stem cells; FGF;

    Sammanfattning : Basement membranes (BMs) are sheet-like structures of extracellular matrix. They act as a supporting structure but can also significantly influence cellular behavior in development, tissue homeostasis and disease. Laminins, a major BM component, are multidomain proteins, consisting of three polypeptide chains (α, β and γ). LÄS MER

  3. 12. Modulation of Angiogenesis by Laminins and Heparan Sulfate

    Författare :Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. LÄS MER

  4. 13. The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development

    Författare :Farshid Jalalvand; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABC-transporter; bacterial colonization; Haemophilus influenzae; Haemophilus Protein F; laminin; NTHi; pathogenesis; vaccine; virulence; vitronectin.;

    Sammanfattning : Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. LÄS MER

  5. 14. Extracellular matrix in atherosclerotic plaques: its role in plaque stability

    Författare :Christoffer Tengryd; Kardiovaskulär forskning - translationella studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix; Laminin; Collagen; Proteoglycans; Atherosclerosis; Carotid plaque; TGF-β;

    Sammanfattning : Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences: myocardial infarctions and stroke. LÄS MER

  7. 15. Human extraocular muscles : molecular diversity of a unique muscle allotype

    Författare :Daniel Kjellgren; Fatima Pedrosa-Domellöf; Lars-Erik Thornell; Lillemor Wachtmeister; John Porter; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; extraocular; muscle; myosin; protein c; laminin; serca; immunocytochemistry; human; Oftalmiatrik; Ophtalmology; Oftalmologi; oftalmiatrik; Ophtalmology;

    Sammanfattning : Introduction: The extraocular muscles (EOMs) are considered a separate class of skeletal muscle, allotype. Myosin is the major contractile protein in muscle. The myosin heavy chain (MyHC) isoforms are the best molecular markers of functional heterogeneity of muscle fibers. LÄS MER