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1. 1. Role of tartrate-resistant acid phosphatase in bone remodeling

   Författare :Laia Mira-Pascual; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tartrate-resistant acid phosphatase is a metalloenzyme that exists as two isoforms: the monomeric TRAP 5a and the proteolytically cleaved TRAP 5b, responsible for phosphatase activity, which is highly expressed in osteoclasts (OCs). TRAP 5b has been used as a serum marker of bone resorption, as it correlates with the absolute number of OCs and with resorption markers such as CTX-I. LÄS MER