Visar resultat 1 - 5 av 684 avhandlingar innehållade ordet LYMPHOCYTES.

  1. 1. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Författare :Carina Lundqvist; Marie-Louise Hammarström; Sten Hammarström; Per Brandtzaeg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER

  2. 2. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Författare :Silvia Melgar; Nadine Cerf-Bensussan; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER

  3. 3. On CD4+ T Lymphocytes in Solid Tumours

    Författare :Per Marits; Ola Winqvist; Magnus Thörn; Alex Karlsson-Parra; Uppsala universitet; []
    Nyckelord :Molecular medicine; Tumour immunology; T lymphocytes; sentinel node detection; colon cancer; urinary bladder cancer; adoptive immunotherapy; Molekylärmedicin;

    Sammanfattning : This thesis deals with recognition and elimination of tumours by T lymphocytes and their use in adoptive immunotherapy.The first tumour-draining lymph node; the sentinel node, is identified by peritumoural injection of a tracer. This is the hypothesised location for the activation of tumour-reactive lymphocytes. LÄS MER

  4. 4. Generation of lymphocytes in the thymus : a study of morphologic, antigenic and functional development of lymphocytes in embryonic thymus organ cultures

    Författare :Roger Juhlin; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 5. T lymphocytes in Wegener’s granulomatosis

    Författare :Ricardo Antonio Giscombe Stephen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Wegener s granulomatosis; T lymphocytes; TCR; T cell expansions; HLA-DRB1*0401; CTLA-4; IL-10;

    Sammanfattning : Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects small and medium size blood vessels. The respiratory tract and lungs are usually compromised with necrotizing granulomatous formations. The aetiology is unknown and untreated the prognosis of generalised WG is very poor. LÄS MER