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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

1. 1. The role of the thromboinflammatory response under hemolytic conditions : pathophysiological mechanisms and therapeutic inhibition

   Författare :Alexandra Gerogianni; Per H. Nilsson; Camilla Mohlin; Tom Eirik Mollnes; Kristina Nilsson Ekdahl; Mihály Józsi; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolysis; heme; thromboinflammation; biomaterials; complement inhibition; LVAD; IONPs; Biomedical Sciences; Biomedicinsk vetenskap; Immunologi; Immunology;

   Sammanfattning : In blood circulation, the complement and the coagulation cascades, together with platelets and endothelial cells form a complex network of crosstalk. When dysregulated, these interactions can lead to inflammation in combination with thrombosis (thromboinflammation) and the manifestation of pathophysiological complications. LÄS MER

3. 2. A minimally invasive axial blood flow pump : an experimental and clinical study

   Författare :Urban Lönn; Howard Frazier; Linköpings universitet; []
   Nyckelord :Axial blood flow pump; Hemopump; LVAD; Beating heart CABG; MEDICINE; MEDICIN;

   Sammanfattning : The first aim of this thesis was to evaluate a new minimally invasive axial blood flow pump for treatment of patients needing circulatory support after open heart surgery. This system, the Hemopump temporary cardiac assist device, is a very small catheter mounted intracorporeal pump, which is introduced transvalvularly into the left ventricle. LÄS MER

4. 3. Treatment of Right Ventricular Failure through Partial Volume Exclusion : An Experimental Study

   Författare :Per Vikholm; Laila Hellgren; Lund Lars; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Right Heart Failure; Left Ventricular Assist Device; Glenn shunt; Thorax Surgery; Thoraxkirurgi;

   Sammanfattning : Implantation of a left ventricular assist device (LVAD) is a potential treatment in terminal heart failure. Right ventricular (RV) failure is a severe complication in these patients and sometimes requires additional placement of a right ventricular assist device (RVAD). LÄS MER

5. 4. Heart failure : advanced treatments and novel hormonal responses

   Författare :Stanislava Zabarovskaja; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Heart failure (HF) affects 2-3% of the Western population and is associated with a 1 year mortality of 20%. Despite therapeutic advances over the last decades, numerous unanswered questions remain regarding the impact of currently established therapies as well as potential new targets for therapy. Aims to investigate: 1. LÄS MER

7. 5. Between the Probe and the Pump : An experimental study on cardiac performance analysis based on Echocardiography, tissue and laser Doppler

   Författare :Laila Hübbert; Birgitta Janerot-Sjöberg; Ulf Dahlström; Sven-Erik Ricksten; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Echocardiography is an ultrasound-based bedside, non-invasive and easily available cardiac diagnostic technique visualising the heart’s morphology and function. Quantification of cardiac wall motion can be measured with the tissue Doppler Imaging (TDI) modality which provides in humans a high diagnostic capacity to differentiate healthy from diseased myocardium with reduced function. LÄS MER