Sökning: "LPA"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet LPA.

  1. 1. Effects of grinding variables on structural changes and energy conversion during mechanical activation using line profile analysis (LPA)

    Författare :Parviz Pourghahramani; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mineralteknik; Mineral Processing;

    Sammanfattning : The mechanical treatment of solids is one of the most common and widely used operations with which man has been concerned from the very beginnings of history of civilization. At the present, mechanical activation has a wide range of application potential. LÄS MER

  3. 2. Renal cell death in urinary tract infections : role of E. coli toxins

    Författare :Ming Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pyelonephritis; Escherichia coli toxins; ERK; LPA; cell death; carbon monoxide; hemolysin; nitric oxide; heme oxygenase-1; dexamethasone; kidney development;

    Sammanfattning : Febrile urinary tract infections (UTI) are common bacterial illnesses in children. Several follow up studies have shown that 10-15 % of infants with pyelonephritis will develop permanent renal damage, i.e., renal scars, which in turn may lead to chronic diseases such as hypertension and renal insufficiency. LÄS MER

  4. 3. Lysophosphatidic acid : Physiological effects and structure-activity relationships

    Författare :Ulrika K. Nilsson; Samuel Svensson; Karin E. Bornfeldt; Linköpings universitet; []
    Nyckelord :Lysophospholipids pharmacology; physiology; structure-activity relationship; muscle; smooth; drug effects; myometrium; norepinephrine; epinephrine; signal transduction; MEDICINE; MEDICIN;

    Sammanfattning : Lipids havepreviously been considered primarily as building blocks of the cell membrane, but are now also recognized as important cell signaling molecules. Lysophosphatidic acid (LPA) is a glycerophospholipid consisting of a phosphate head group, a linker region, and a lipophilic tail. LÄS MER

  5. 4. Regulatory importance of cyclic nucleotides in smooth muscle growth of the urogenital tract

    Författare :Per Adolfsson; Thoralf Christoffersen; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Smooth muscle hyperplasia/hypertrophy is, if not responsible for, so at least involved in those diseases, which impair life quality for most people in today's society.This thesis, presents a pharmacological investigation, related to the regulatory role of cyclic nucleotides, of smooth muscle hyperplasia/hypeitrophy in human uterine leiomyoma and benign prostate hyperplasia (BPH). LÄS MER

  7. 5. Chronic pain and arthritis : studies of mechanisms in the regulation of hypersensitivity

    Författare :Jie Su; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic pain is one of the most devastating symptoms reported by rheumatoid arthritis (RA) patients. Current treatment strategies are focusing on dampening the inflammatory and immunological aspects of RA, but unfortunately subgroups of patients continue to suffer from pain, even when the disease is adequately controlled. LÄS MER