Sökning: "LOCALIZES"

Visar resultat 1 - 5 av 61 avhandlingar innehållade ordet LOCALIZES.

  1. 1. Characterization of the inner nuclear membrane protein Samp1, during interphase and mitosis

    Författare :Veronica J. Larsson; Einar Hallberg; Katharine S. Ullman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Samp1; LINC complex; nuclear lamina; MCLIP; nuclear envelope; spindle assembly; spindle stability; k-fiber; gamma tubulin; Aurora B; Haus6; Augmin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nucleus, a hallmark in eukaryotic cells, contains the genome separating it from molecules in the cytoplasm. The nucleus is surrounded by a nuclear envelope consisting of two concentric membranes, the outer nuclear membrane and the inner nuclear membrane, the nuclear lamina and nuclear pore complexes. LÄS MER

  3. 2. TRIM22/Staf50 - a novel target gene of the tumor suppressor p53

    Författare :Susanna Obad; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; T lymphocyte; apoptosis; PML; differentiation; hematopoiesis; leukemia; interferon; p53; TRIM22 Staf50; extracellulära vätskor;

    Sammanfattning : The tumor suppressor gene p53 is a transcription factor that mediates cell cycle arrest, apoptosis and differentiation. p53 mediated differentiation of leukemic cells depends on the transcriptional activity of p53 but so far no obvious differentiation inducing target gene has been identified. LÄS MER

  4. 3. An approach to extraction of pipeline structures for VLSI high-level synthesis

    Författare :Björn Fjellborg; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : One of the concerns in high-level synthesis is how to efficiently exploit the potential concurrency in a design. Pipelining achieves a high degree of concurrency, and a certain structural regularity through exploitation of locality in communication. However, pipelining cannot be applied to all designs. LÄS MER

  5. 4. In vivo analysis of amino acid permease folding in yeast

    Författare :Andreas Ring; Per O. Ljungdahl; George Diallinas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nutrient sensing; signal transduction; endoprotease; subcellular fractionation; membrane-localized chaperone; amino acid permease; endoplasmic reticulum; membrane protein folding; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

    Sammanfattning : Plasma membrane (PM) proteins are critical for cells to respond to environmental cues, such as the availability of nutrients. The yeast Saccharomyces cerevisiae is able to sense extracellular amino acids using the SPS sensing system. LÄS MER

  7. 5. Identification and Characterization of Novel Candidate Oncogenes

    Författare :Marina Mencinger; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk genetik; Clinical genetics; RBP56; APRIL; TFG; FUS; EWS; EST database; fusion genes; chromosome; molecular genetics; cancer; Cytology; oncology; cancerology; Cytologi; onkologi;

    Sammanfattning : Using computer-assisted sequence homology searches we identified three genes encoding proteins similar to certain fusion partner proteins in cancer. The novel APRIL gene was localized to 15q25 and encodes a protein, containing an acidic amino-acid region similar to that/those of leukemia-associated fusion partner proteins DEK and SET. LÄS MER