Sökning: "LIM proteins"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden LIM proteins.
1. Genetics of immunoglobulin a deficiency
Sammanfattning : Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasian populations. It is defined as a serum IgA level below 0.07 g/L with normal IgM and IgG levels in an individual older than four years of age. LÄS MER
2. Transcriptional regulation and effects on differentiation by LMO proteins and the basic helix-loop-helix factors TAL1 and HEN1
Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most widespread type of cancer, as well as the most frequent leukemia in children. Malignant ALL cells originate from normal T lymphocytes or B cells that are blocked at immature stages of differentiation. LÄS MER
3. Combined structural methods to characterize an oligomeric small heat shock protein Hsp21
Sammanfattning : Small heat shock proteins (sHsps) are found in all organisms and evolved early in the history of life, prior to the divergence of the three domains of life (Archaea, Bacteria, and Eukarya). Their malfunction is connected to several different diseases in humans, such as Alzheimer’s and Parkinson’s disease. LÄS MER
4. LRIG1 in lung cancer : prognostic effects and mechanistic studies
Sammanfattning : Lung cancer is the leading cause of cancer-related death worldwide as well as in Sweden. Non-small cell lung cancer (NSCLC) is the predominant form, which is largely subdivided into adenocarcinomas and squamous cell carcinomas. LÄS MER
5. Development of improved nuclear magnetic resonance techniques and structure determination of a zinc finger peptide
Sammanfattning : Since the functions of biological molecules are closely related to their structures, obtaining the three-dimensional structures is of great importance to the understanding of biology. Currently, the only two methods that can be used for protein structure determination at atomic resolution are X-ray crystallography and NMR spectroscopy. LÄS MER