Sökning: "LDL particle size"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden LDL particle size.

  1. 1. Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes

    Författare :Camilla Pettersson; Göteborgs universitet; []
    Nyckelord :Type 2 diabetes; metabolic syndrome; atherosclerosis; VLDL; LDL; secretory phospholipase A2 group V; inflammation; complement; apolipoprotein; lysozyme;

    Sammanfattning : Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are associated with an increased risk for developing and dying of cardiovascular disease (CVD). The aim of this thesis was to investigate possible atherogenic properties of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) in T2D and MetS. LÄS MER

  3. 2. Atherogenic lipoproteins and their interaction with proteoglycans

    Författare :Christofer Flood; Göteborgs universitet; []
    Nyckelord :apolipoprotein B; atherosclerosis; LDL; proteoglycan; sPLA2; ; retention;

    Sammanfattning : Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is the initiating event in atherogenesis. LÄS MER

  4. 3. Atherosclerosis and Insulin Resistance AIR A cross-sectional study of 58-year old men

    Författare :Lena Bokemark; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; intima-media thickness; LDL particle size; atherosclerosis.;

    Sammanfattning : The main aim of the study was to test the hypothesis that insulin resistance is associated with atherosclerotic disease in the carotid and femoral arteries as measured using the ultrasound technique in clinically healthy 58-year old men with varying degrees of obesity and insulin resistance. The subjects were recruited from the general population and were free from clinical cardiovascular disease, diabetes mellitus and treatment with antihypertensive, lipid-lowering and anti-diabetic drugs (n=818). LÄS MER

  5. 4. Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome

    Författare :Karin Wallenfeldt; Göteborgs universitet; []
    Nyckelord :apolipoproteins; atherosclerosis; C-reactive protein; insulin resistance; intima-media thickness; LDL cholesterol; longitudinal study; metabolic syndrome X; smokeless tobacco; ultrasonography;

    Sammanfattning : The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those without MetS. Up to one third of the adult population seems to be affected worldwide. LÄS MER

  7. 5. Low density lipoprotein (LDL) heterogeneity : implications for cardiovascular disease and genetic influence

    Författare :Camilla Skoglund Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Low density lipoprotein; gradient gel electrophoresis; intima-media thickness; atherosclerosis; myocardial infarction; low density lipoprotein oxidation; cholesteryl ester transfer protein; lipoprotein lipase; hepatic lipase; apolipoprotein E; apolipoprotein B; microsomal triglyceride transfer protein; genetics; lipoproteins; metabolism;

    Sammanfattning : The low density lipoprotein (LDL) particle population is heterogeneous with regard to several structural and functional properties that may influence its atherogenic potential. A preponderance of small, dense LDL is associated with an increased risk of coronary heart disease (CHD), and also predicts future CHD events. LÄS MER