Sökning: "LCLS"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet LCLS.

  1. 1. Electromagnetic Field Induced Out-of-Equilibrium Structural Dynamics in Protein Crystals: From Picoseconds to Milliseconds

    Författare :Viktor Ahlberg Gagnér; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Terahertz radiation; low frequency vibrations; B-factors; ADP tensor; bovine trypsin; FemtoMAX; resampling; femtosecond structural dynamics; millisecond structural dynamics; LCLS; displacements; distances; photosynthetic reaction center;

    Sammanfattning : Light-induced interactions in biomolecules are strongly varying over different model systems. Most amino acids and proteins absorb ultraviolet light, but only a few with specialised chromophores or fluorophores, are able to absorb light in the visible spectrum. LÄS MER

  3. 2. Early events of EBV mediated B cell transformation

    Författare :Katja Pokrovskaja; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EBV; EBNA; p53; LMP-1; BL; GC; pNDCFs;

    Sammanfattning : Epstein-Barr virus (EBV) efficiently immortalizes B cells in vitro leading to the establishment of lymphoblastoid cell lines (LCLs). Genes encoding RB and p53 are frequently deleted or mutated in human tumors. EBV immortalized LCLs, however, retain both genes in their wild type state. LÄS MER

  4. 3. The role of EBNA binding proteins in cell transformation

    Författare :Suhas Darekar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epstein-Barr virus (EBV) infects majority of the human population and maintains sub-clinical infection. However, under certain conditions it is associated with several B-cell malignancies, such as Burkitt lymphoma, Hodgkin’s lymphoma etc. LÄS MER

  5. 4. X-ray free-electron laser based methods for structural and ultrafast dynamics studies of a photosynthetic reaction centre

    Författare :David Arnlund; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; WAXS; wide-angle x-ray scattering; XFEL; x-ray free-electron laser; reaction center; structural biology; ultrafast dynamics;

    Sammanfattning : Life on earth is fuelled by the energy of sunlight, which must first be captured and converted into a chemical energy form useful to the cell. This process is known as photosynthesis and the major pathway of this energy conversion is via photosynthetic reaction centres. LÄS MER

  7. 5. Antigen interaction with B cells in two proliferative disorders : CLL and MGUS

    Författare :Eva Hellqvist; Anders Rosén; Jan Ernerudh; Anne Mette Buhl; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The aim of the work presented in this thesis was to elucidate B cell interaction with antigen in the two B cell proliferative disorders chronic lymphocytic leukemia (CLL) and monoclonal gammopathy of undetermined significance (MGUS). In the first part we investigated the antigen specificity of CLL cells and characterized Epstein-Barr virus (EBV)-transformed CLL cell lines with regard to phenotype and genotype. LÄS MER