Sökning: "LC GC MS"

Visar resultat 11 - 15 av 39 avhandlingar innehållade orden LC GC MS.

  1. 11. Maternal and neonatal metabolomes and their associations to immune maturation and allergy in early life

    Författare :Olle Hartvigsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Untargeted Metabolomics; allergy; QC; quality control; plasma; umbilical cord; placenta; LC-MS; immune system;

    Sammanfattning : Allergy, one of the most common chronic diseases worldwide, is caused by a dysregulated immune system reacting to normally harmless proteins. However, regulating mechanisms are not well understood. The aim of this thesis was to investigate if plasma and placenta metabolites associate prospectively to allergy development and immune maturation. LÄS MER

  3. 12. Engineering synthetic pathways for adipic acid biosynthesis

    Författare :Jae Ho Shin; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; cell factory; Corynebacterium glutamicum; L-lysine; GC MS; lignocellulose; adipic acid; benzoic acid; pathway engineering; muconic acid; cultivation; analytical chemistry; in silico docking;

    Sammanfattning : Utilization of petroleum in consumer product manufacturing is causing irreversible environmental damage. Its impact on land, sea, and air calls for the development of more sustainable technologies based on the use of renewable materials such as lignocellulosic biomass and its conversion into platform chemicals. LÄS MER

  4. 13. Fundamental Aspects of Lignin Carbohydrate Complexes (LCC) : Mechanisms, Recalcitrance and Material concepts

    Författare :Nicola Giummarella; Martin Lawoko; Gunnar Henriksson; Arthur J. Ragauskas; KTH; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Lignin Carbohydrates Complexes; Phenyl Glycosides; Benzyl Ethers; Benzyl and γ-esters; Universal Mild Quantitative fractionation; LCC mechanism formation; Extracellular lignin; Dehydogenation polymer; Autohydrolysis; Recalcitrance; Acetylation role; HSQC; HMBC; HSQC-TOCSY; 13C; 31P NMR; Thioacidolysis-GC; SEC; Green; Biomimetic; One-pot-lignin functionalization; Lignin platform material.; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Covalent bonds between lignin and carbohydrates, forming a matrix referred to as lignin carbohydrate complexes (LCC), remain one of the most controversial topics in wood chemistry. A key issue is whether they are formed during chemical and mechanical pretreatments of the compact wood structure or actually present in wood prior to isolation. LÄS MER

  5. 14. New approaches for synthesis and analysis of adducts to N-terminal valine in hemoglobin from isocyanates, aldehydes, methyl vinyl ketone and diepoxybutane

    Författare :Ronnie Davies; Margareta Törnqvist; Leif Kronberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbamoylation; modified-Edman procedure; 5- hydroxymethyl furfural; MISPE; biomarkers; Environmental chemistry; Miljökemi; miljökemi; Environmental Chemistry;

    Sammanfattning : Human exposure to harmful compounds in the environment, from intake via food, occupational exposures or other sources, could have health implications. Exposure to reactive compounds/metabolites can be identified and quantified as hemoglobin (Hb) adducts by mass spectrometry. LÄS MER

  7. 15. Advances in Mass Spectrometry for the Analysis of Emerging Persistent Organic Pollutants

    Författare :Lauren Gayle Mullin; Leo W. Y. Yeung; Ingrid Ericson Jogsten; Jean-François Focant; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Liquid Chromatography; Supercritical Fluid Chromatography; Ion Mobility; POPs; Electrospray Ionization;

    Sammanfattning : Mass spectrometry (MS) is a technique widely implemented for the measurement of environmental pollutants. A critical tool for the analysis of persistent organic pollutants (POPs) over several decades, MS as coupled with liquid and gas chromatography (LC and GC) techniques enables the analysis of emerging POPs. LÄS MER