Sökning: "L-DOPA induced dyskinesia"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden L-DOPA induced dyskinesia.

  1. 21. Neuroplasticity and neurorestoration in the treatment of Parkinson's Disease: Experimental studies in the mouse

    Författare :Veronica Francardo; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Neuroplasticity is the brain´s capacity to respond to inner and outer challenges with functional and structural reorganizations. An aberrant activation of neuroplasticity pathways may contribute to the development of neurological disease. LÄS MER

  3. 22. Striatal signaling in the treatment of Parkinson's disease

    Författare :Irene Sebastianutto; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Parkinson’s disease (PD) is a neurodegenerative disorder characterized by typical motor symptoms that are caused by depletion of dopamine (DA) in the striatum. These symptoms are treated with the DA precursor L-DOPA, or with DA receptor (DAR) agonists. LÄS MER

  4. 23. Mechanisms of motor and non-motor complications in experimental parkinsonism

    Författare :Carina Plewnia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Parkinson’s disease (PD), one of the most common neurodegenerative disorders, is classically characterized by the progressive loss of midbrain dopaminergic neurons and by the emergence of cardinal motor symptoms including rigidity, tremor and bradykinesia. PD treatment relies on pharmacological dopamine replacement, which is the most effective therapy to alleviate motor symptoms. LÄS MER

  5. 24. Cerebrum Illuminans : Mass Spectrometric Analysis of Protein and Peptide Dynamics in Neurological Diseases

    Författare :Jörg Hanrieder; Jonas Bergquist; Malin Andersson; Ulf Hellman; Alma Burlingame; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; central nervous system; neurological disease; proteomics; MALDI imaging; Analytical chemistry; Analytisk kemi; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : The human brain (lat. cerebrum) is the most complex and heterogeneous organ in the human body. It is involved in a great number of body functions like movement, touch sensing, vision, hearing, smelling, hormone regulation and many more. In no other organ, the molecular communication mechanisms between different cells are so poorly understood. LÄS MER

  7. 25. Bridging the gap between lipid dyshomeostasis and brain disorders : role of prosaposin and progranulin

    Författare :Yachao He; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Brain tissue is the second-highest lipid-containing tissue after adipose in the human body. Lipid homeostasis maintenance requires the coordination of multiple cellular organelles. Pathogenesis of brain disorders, especially Parkinson’s disease (PD), usually involves different dysfunctional pathways that intimately link to lipid homeostasis. LÄS MER