Sökning: "L Wide"
Visar resultat 1 - 5 av 161 avhandlingar innehållade orden L Wide.
Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER
Sammanfattning : Most proteomics and genomics experiments are performed on a small set of well-studied model organisms and their results are generalized to other species. This is possible because all species are evolutionarily related. When transferring information across species, orthologs are the most likely candidates for functional equivalence. LÄS MER
Sammanfattning : Cochlear hearing loss leads to deficits in many perceptual aspects, including threshold elevation (loss of sensitivity), reduction of auditory dynamic range (loudness recruitment) and problems with resolving sounds (loss of supra-threshold hearing). An ongoing debate is whether assessment of the individual supra-threshold hearing provides information which is likely to have an important influence on clinical decisions on signal processing strategies. LÄS MER
Sammanfattning : This thesis deals with control aspects of complex hydromechanical transmissions. The overall purpose is to increase the knowledge of important aspects to consider during the development of hydromechanical transmissions to ensure transmission functionality. LÄS MER
Sammanfattning : Mucopolysaccharidosis type II or Hunter syndrome is a rare lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS). The disorder is inherited in an X-linked recessive fashion and has a broad spectrum of clinical phenotypes ranging from severe to mild. LÄS MER