Sökning: "L Roos"

Hittade 3 avhandlingar innehållade orden L Roos.

  1. 1. Structural and Functional Studies of Ribose-5-phosphate isomerase B

    Författare :Annette K. Roos; Sherry L. Mowbray; Torsten Unge; Constance Jeffery; Uppsala universitet; []
    Nyckelord :Molecular biology; Mycobacterium tuberculosis; reaction mechanism; cis-enediolate high energy intermediate; allose-6-phosphate isomerase; rare sugar; pentose phosphate pathway; Rv2465c; X-ray crystallography; Molekylärbiologi;

    Sammanfattning : Ribose 5-phosphate isomerase (Rpi) is one of the major enzymes of the pentose phosphate pathway, where it catalyses the inter-conversion of ribose 5-phosphate (R5P) and ribulose 5-phosphate. Two forms of this isomerase with no significant amino acid sequence similarity exist, RpiA and RpiB. LÄS MER

  3. 2. The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta

    Författare :Sara Roos; Göteborgs universitet; []
    Nyckelord :amino acids; fetal growth restriction; human; mammalian target of rapamycin; membrane transporters; metabolism; placenta; pregnancy; system A; system L; taurine transporter;

    Sammanfattning : Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there is no specific treatment of this condition. LÄS MER

  4. 3. Stable high-sensitivity cardiac troponin T levels and outcomes

    Författare :Andreas Roos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Many patients who seek medical attention because of chest pain in the emergency department (ED), without myocardial infarction (MI) as a final diagnosis, will have cardiac troponin (cTn) levels above the upper normal limit when measured with the high-sensitivity cardiac troponin T (hs-cTnT) assay. In patients with acute medical diseases other than MI which may affect hs-cTn levels, treatment strategies focus on underlying conditions. LÄS MER