Sökning: "L Li"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden L Li.

  1. 1. Exposure to inorganic arsenic in pregnancy and metabolism-nutrition interaction

    Författare :Li Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inorganic arsenic is metabolized by most mammals, including humans, via alternating reduction and oxidative methylation with S-adenosylmethionine as main methyl donor. Thus, it seems likely that it is influenced by the availability of methyl groups. LÄS MER

  3. 2. Conformationally Constrained Oligonucleotides for RNA Targeting

    Författare :Qing Li; Jyoti Chattopadhyaya; Li-He Zhang; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; conformationally constrained nucleoside; antisense oligonucleotide; RNA affinity; nuclease stability; RNase H; RNA degradation; Chemistry with specialization in Bioorganic Chemistry; Kemi med inriktning mot bioorganisk kemi;

    Sammanfattning : A short oligonucleotide sequence as in a single-stranded antisense oligo nucleotides (AON) or in double-stranded small interfering RNAs (siRNA) can modulate the gene expression by targeting against the cellular mRNA, which can be potentially exploited for therapeutic purposes in the treatment of different diseases. In order to improve the efficacy of oligonucleotide-based drugs, the problem of target affinity, nuclease stability and delivery needs to be addressed. LÄS MER

  4. 3. Optical absorption in amorphous Li(x)WO(y)

    Författare :L. Berggren; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Evidence for adaptive variation at the genes coding for cytosolic phosphoglucose isomerase (PGIC) in Festuca ovina L

    Författare :Yuan Li; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 3-D protein structure; purifying selection; positive selection; cDNA sequences; local adaptation; alvar grasslands; Festuca ovina; Phosphoglucose isomerase; PgiC loci; SNPs; nucleotide polymorphism; horizontal gene transfer;

    Sammanfattning : The gene (Pgi) encoding the enzyme phosphoglucose isomerase (PGI) which plays a central role in the main pathways of carbon metabolism has been shown to be of adaptive significance in a wide range of different species. Earlier studies of enzyme electromorph variation in the grass Festuca ovina suggest that variation in cytosolic PGI (PGIC) may be involved in the adaptive response of F. LÄS MER

  7. 5. Bonding and Diffusion of Molecules in Zeolites by ESR and ENDOR

    Författare :Haitao Li; Eli Olaug Hole; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis studies bonding and diffusion of molecules in zeolites by Electron Spin Resonance (ESR) and Electron Nuclear Double Resonance (ENDOR). In the first part an introduction is given. In the second part (chapter 2) the detailed structure of a Cu2+ complex with water molecules in Cu-ZSM-5 zeolite was characterized with ENDOR at 4 K. LÄS MER