Sökning: "Kristofer Olofsson"
Hittade 1 avhandling innehållade orden Kristofer Olofsson.
1. Regiocontrol in the Heck-reaction and fast fluorous chemistry
Sammanfattning : The palladium-catalysed Heck-reaction has been utilised in organic synthesis, where the introduction of aryl groups at the internal, β-carbon of different allylic substrates has been achieved with high regioselectivity.The β-stabilising effect of silicon enhances the regiocontrol in the internal arylation of allyltrimethylsilane, while a coordination between palladium and nitrogen induces very high regioselectivities in the arylation of N,N-dialkylallylamines and the Boc-protected allylamine, producing β-arylated arylethylamines, which are of interest for applications in medicinal chemistry. LÄS MER