Sökning: "Kristin karlsson"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Kristin karlsson.

  1. 1. Benefits of Pharmacometric Model-Based Design and Analysis of Clinical Trials

    Författare :Kristin E Karlsson; E Niclas Jonsson; Mats O Karlsson; Anders Grahnén; Michael K Smith; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; model-based analysis; pharmacometrics; modeling; disease progression; NONMEM; SAEM; Importance sampling; repeated time-to-event; RTTCE; RCEpT; NIH stroke scale; Barthel index; internal validation; external validation; study power; study design; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Quantitative pharmacokinetic-pharmacodynamic and disease progression models are the core of the science of pharmacometrics which has been identified as one of the strategies that can make drug development more effective. To adequately develop and utilize these models one needs to carefully consider the nature of the data, choice of appropriate estimation methods, model evaluation strategies, and, most importantly, the intended use of the model. LÄS MER

  3. 2. Fastighetens gränser

    Författare :Kristin Land; Former name: Kristin Karlsson; Fastighetsvetenskap; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Lantmäteriverket har uttryckt en vision om koordinatbestämda fastighetsgränser, med avsikt att skapa en i gränshänseende korrekt digital registerkarta. Ett förverkligande av visionen skulle kräva en förändring av gällande rätt, eftersom dagens gränssystem bygger på principen att gränsmärken på marken gäller framför andra uppgifter om gränsers sträckning. LÄS MER

  4. 3. Characterisation of pollutants in stormwater treatment facilities

    Författare :Kristin Karlsson; Davis Butler; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VA-teknik; Urban Water Engineering;

    Sammanfattning : The overall objective of this thesis is to increase the knowledge of both the pollutants within stormwater treatment facilities and the maintenance of these facilities. This objective has been achieved by studying water and sediment with respect to metal concentrations, fractionation, and toxicity from ponds, sedimentation tanks, and gully pots with different catchment characteristics as well as from the sediment removal process. LÄS MER

  5. 4. Pathways of pollutants in stormwater systems

    Författare :Kristin Karlsson; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VA-teknik; Urban Water Engineering;

    Sammanfattning : The choice of stormwater procedures will affect the pathways of the water and its pollutants, since different stormwater facilities reduce different types of substances and fractions to varying degrees. Traditional stormwater handling has mainly been emphasised to transport the water from the cities. LÄS MER

  7. 5. Stereotactic body radiation therapy of lung tumours : clinical and dosimetric aspects

    Författare :Kristin Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The general aim of this thesis was to increase the knowledge regarding some clinical and methodological aspects, relevant in view of toxicity as well as tumour control, in stereotactic body radiation therapy (SBRT) of lung tumours. In the first two studies, reirradiation and radiation-induced atelectasis were studied. LÄS MER