Sökning: "Kristian Pirttilä"

Hittade 1 avhandling innehållade orden Kristian Pirttilä.

1. 1. Development of analytical methods for the determination of the small molecule component of complex biological systems

   Författare :Kristian Pirttilä; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Thomas Moritz; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolomics; data processing; peak characterization; algorithm; multivariate data analysis; chromatography; sequential columns; HILIC; RPLC; liquid chromatography; mass spectrometry; LC; MS; noise-induced hearing loss; NIHL; guinea pig; perilymph; method development; validation; R; C ; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Sammanfattning : The research field of untargeted metabolomics aims to determine the relative abundance of all small metabolites in a biological system in order to find biomarkers or make biological inference with regards to the internal or external stimuli. This is no trivial aim, as the small metabolites are both vast in numbers and extremely diverse in their chemical properties. LÄS MER