Sökning: "Kp"
Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet Kp.
1. Physiologically Based Pharmacometric Models for Colistin and the Immune Response to Bacterial Infection
Sammanfattning : Antibiotic treatment failure might be due to bacterial resistance or suboptimal exposure at target site and there is a lack of knowledge on the interaction between antimicrobial pharmacodynamics (PD) and the immune response to bacterial infections. Therefore, it is crucial to develop tools to increase the understanding of drug disposition to better evaluate antibiotic candidates in drug development and to elucidate the role of the immune system in bacterial infections. LÄS MER
2. Immunometabolic network interactions of the kynurenine pathway in cutaneous malignant melanoma
Sammanfattning : Cancer is the second leading cause of mortality worldwide, and melanoma represents the most aggressive and deadliest form of skin cancer. Despite the various therapeutic approaches, metastatic melanoma is a disease with a poor prognosis. LÄS MER
3. Advocates and Voices. Swedish patient associations, their importance to individuals with cancer and collaboration with health care
Sammanfattning : Patient associations (PAs) have an increasing impact for their members and for the health care system. This thesis studies PAs for cancer patients (PACPs) ? currently with over 20 000 members in Sweden ? regarding coverage, activities, and collaboration with the health care system with specific reference to the members? experiences. LÄS MER
4. Every bug counts : neonatal colonization and infection of Gram-negative bacilli : aspects on antibiotic resistance in Sweden and Ecuador
Sammanfattning : Neonatal infections caused by extended-spectrum beta-lactamase (ESBL)-producing Gramnegative bacilli are associated with high morbidity and mortality. In order to perform targeted preventive interventions against the impacts of antibiotic resistance in neonates, it is crucial to study colonization, infection and the spread of EPE-bacteria. LÄS MER
5. Mechanisms of inter-organ crosstalk mediated by tryptophan metabolism
Sammanfattning : Physical exercise and nutrition balance the “energy in-energy out” equilibrium that keeps the system at a dynamic homeostasis, energetically speaking. However, this is a simplistic vision of a dynamic system that is in a constant fine-tuning of all of its parts. LÄS MER