Sökning: "Kluyveromyces lactis γ-toxin"

Hittade 2 avhandlingar innehållade orden Kluyveromyces lactis γ-toxin.

  1. 1. The Kluyveromyces lactis killer toxin is a transfer RNA endonuclease

    Författare :Jian Lu; Anders Byström; Leif Kirsebom; Umeå universitet; []
    Nyckelord :Molecular biology; K. lactis γ-toxin; tRNA endonuclease; modified nucleosides; 5-methoxycarbonylmethyl-2-thiouridine; 5-methylaminomethyl-2-thiouridine; anticodon stem loop; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Killer strains of the yeast Kluyveromyces lactis secrete a heterotrimeric protein toxin (zymocin) to inhibit the growth of sensitive yeasts. The cytotoxicity of zymocin resides in the γ subunit (γ-toxin), however the mechanism of cytotoxicity caused by γ-toxin was previously unknown. LÄS MER

  2. 2. Functional aspects of wobble uridine modifications in yeast tRNA

    Författare :Anders Esberg; Anders Byström; James T. Anderson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Transfer RNA; Modified nucleosides; Elongator complex; Translation; Kluyveromyces lactis γ-toxin; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Transfer RNAs (tRNA) function as adaptor molecules in the translation of mRNA into protein. These adaptor molecules require modifications of a subset of their nucleosides for optimal function. The most frequently modified nucleoside in tRNA is position 34 (wobble position), and especially uridines present at this position. LÄS MER