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Visar resultat 1 - 5 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Evolutionary trajectories of Klebsiella pneumoniae : From experimental biofilm evolution to a hospital outbreak

    Författare :Greta Zaborskytė; Linus Sandegren; Vaughn S. Cooper; Uppsala universitet; []
    Nyckelord :Klebsiella pneumoniae; evolution; experimental evolution; biofilms; infection; bacterial pathogens; Mikrobiologi; Microbiology;

    Sammanfattning : Bacterial evolution is closely intertwined with our lives. As their hosts, we shape how bacteria evolve by imposing numerous selective pressures during the time bacteria spend in our bodies. As a result, they adapt in various ways to colonize us or infect us better. LÄS MER

  3. 2. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Författare :Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Sammanfattning : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. LÄS MER

  4. 3. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli

    Författare :Harald Eriksson; Anders Nilsson; Elisabeth Haggård-Ljungquist; Klas Flärdh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacterial viruses; Bacteriophage; Phage; Phage therapy; multi-resistant bacteria; Klebsiella pneumoniae; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. LÄS MER

  5. 4. Evolution of beta-lactam : resistance in Klebsiella pneumoniae

    Författare :Sara Hæggman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : K. pneumoniae is recognized as a common opportunistic pathogen. Numerous reports have been published worldwide on outbreaks in different healthcare settings. K. LÄS MER

  7. 5. Characterisation of Food Associated Bacteria by DNA based Methods, with Special Reference to Enterobacteriaceae

    Författare :Crister Olsson; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; 16S rRNA; TTGE; ribotyping; Rahnella; Klebsiella; HPI; Enterobacteriaceae; food; Livsmedelsteknik;

    Sammanfattning : The presence of genes in food, encoding some virulence factors, was studied by PCR, and species of Enterobacteriaceae, associated with food, were studied by the DNA-based methods of TTGE, ribotyping and sequencing. The flora of fresh and chill-stored pork were analysed by a culture-independent approach, using specific amplification of 16S rRNA genes followed by cloning and sequencing. LÄS MER