Sökning: "Klaus Erixon"

Hittade 5 avhandlingar innehållade orden Klaus Erixon.

  1. 1. DNA excision repair in mammalian cells

    Författare :Klaus Erixon; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 2. Interplay between DNA repair pathways at replication forks in mammalian cells

    Författare :Fredrik Johansson; Dag Jenssen; Klaus Erixon; Harry Vrieling; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; Toxikologi;

    Sammanfattning : Cellular DNA is continuously being damaged by various agents of both endogenous and exogenous origin including a wide range of chemical compounds, UV-light and ionizing radiation. In order to remove lesions from the DNA and maintain genomic stability, different repair processes have evolved. LÄS MER

  4. 3. Factors Influencing the Yield of Mutations Induced by Polycyclic Aromatic Hydrocarbons in Mammalian Cells

    Författare :Anne Lagerqvist; Dag Jenssen; Klaus Erixon; Fredrik Johansson; Hanspeter Naegeli; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; Toxikologi; toxikologisk genetik; Toxicological Genetics;

    Sammanfattning : Environmental contaminants are ubiquitously present in the urban environment, this has the implication that humans are exposed to toxic and carcinogenic chemicals. Polycyclic aromatic hydrocarbons (PAH) are one type of environmental contaminants, which are produced by combustion of organic compounds. LÄS MER

  5. 4. Homologous recombination at replication forks in mammalian cells

    Författare :Cecilia Lundin; Thomas Helleday; Klaus Erixon; Keith W. Caldecott; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Genetik;

    Sammanfattning : Accumulating evidence indicates that homologous recombination plays an important role in mammalian cells, primarily in the reactivation of stalled replication forks. During a normal round of replication, stalling of the replication fork occurs frequently when a nick or a lesion, which cannot be by-passed, is encountered. LÄS MER

  7. 5. Interstrand Crosslinks - Induction and repair

    Författare :Daniel Vare; Dag Jenssen; Klaus Erixon; Fredrik Johansson; Marcel Tijsterman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ICL; DNA repair; interstrand crosslink; psoralen; molekylärgenetik; Molecular Genetics;

    Sammanfattning : DNA crosslinking agents exhibit a variety of DNA lesions, such as monoadducts, DNA-DNA interstrand or intrastrand crosslinks or DNA-protein crosslinks. Agents that produce interstrand crosslinks (ICLs) exist naturally and are widely used in chemotherapy. Therefore, it is important to understand how the lesions induced by these agents are repaired. LÄS MER