Sökning: "Kiran Yanamandra"

Hittade 1 avhandling innehållade orden Kiran Yanamandra.

1. 1. Studies of in vivo prostate amyloidosis and autoimmune responses towards amyloid structures in neurodegeneration

   Författare :Kiran Yanamandra; Ludmilla Morozova-Roche; Dina Raveh; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; amyloidosis; immune reactivity; S100A8 A9; insulin; α-synuclein; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : By using multidisciplinary analysis of CA inclusions in prostate glands of patients diagnosed with prostate cancer, we have revealed that their major components are the amyloid forms of S100A8 and S100A9 proteins associated with numerous inflammatory conditions and types of cancer. We have demonstrated that material closely resembling CA can be produced from S100A8/A9 in vitro and shows the characters of amyloids. LÄS MER