Sökning: "Ki-67"

Visar resultat 16 - 20 av 82 avhandlingar innehållade ordet Ki-67.

1. 16. Assessment of diagnostic and prognostic factors in pancreatic duct carcinoma

   Författare :Stefan Linder; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Pancreatic neoplasms; cytology; diagnosis; prognosis; DNA ploidy; morphometry; immunohistochemistry; Ki-67 antigen; p53 protein; ECM proteins; adhesion molecules.;

   Sammanfattning : The diagnosis pancreatic carcinoma is suggested by a combination of clinical and radiological signs. The differential diagnosis vs. chronic pancreatitis may, however, be difficult. Morphological verification of malignancy is therefore necessary before initiating non-surgical therapy. LÄS MER

3. 17. Development of squamous cell carcinoma in venous ulcers

   Författare :Baldur Baldursson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :cancer epidemiology; human papillomavirus; p53; p21; bc1-2; Ki-67; wound healing; chronic ulcers; skin carcinogenesis; growth factors;

   Sammanfattning : Apart from numerous case reports, studies on the epidemiology and the outcome of malignant transformation in venous leg ulcers are scarce. Even the aetiology is unsettled, and the genetic effects of the chronic ulcer state only partly studied. LÄS MER

4. 18. Synovial sarcoma : a Scandinavian sarcoma group project

   Författare :Björn Skytting; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :synovial sarcoma; prognosis; tumor size; poorly differentiated; histologic grading; Ki-67; proliferation; CGH; secondary aberrations; RT-PCR; translocation; SYT-SSX1 SYT-SSX2;

   Sammanfattning : Synovial sarcoma accounts for 5 to 10 % of all soft tissue sarcomas. More than 90 % are found in the extremities or trunk wall. Characteristic for synovial sarcoma is the translocation t(X; 18) (p11.2;q11. LÄS MER

5. 19. Quantitative cellular methods in the evaluation of prostate cancer

   Författare :Naining Wang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :prostate cancer; histopathology; nuclear morphology; DNA ploidy; S-phase fraction; thymidine kinas; Ki-67; cell proliferation; fluorescence cytometry; tissue PSA; prognosis;

   Sammanfattning : The distinction between those prostate cancers rapidly progressing and leading to death and those with little likelihood of causing death in cancer is a major goal in current prostate cancer research. Morphological tumor characteristics at present are the basis for evaluation of the prognosis of the disease. LÄS MER

7. 20. Glioblastoma multiforme in the microscope: Diagnostic features of importance for prognosis and treatment

   Författare :Annette Persson; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; cytogenetik; Genetik; Genetics; cytogenetics; Medicin människa och djur ; macrophages; adenoviral based gene-therapy proliferation activity; telomerase activity; immunohistochemistry; Medicine human and vertebrates ; cytotoxic T-lymphocytes; diagnostic features; prognosis; immuno-therapy; Glioblastoma multiforme; neuropathology; pathological anatomy; Patologi allmän ; patologisk anatomi;

   Sammanfattning : Glioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. LÄS MER