Sökning: "Ki Bok Min"

Visar resultat 1 - 5 av 213 avhandlingar innehållade orden Ki Bok Min.

  1. 1. Determination of equivalent hydraulic and mechanical properties of fractured rock masses using the distinct element method

    Författare :Ki-Bok Min; KTH; []
    Nyckelord :equivalent continuum approach; equivalent property; representative elementary volume; distinct element method;

    Sammanfattning : The equivalent continuum approach uses equivalent propertiesof rock mass as the input data for a continuum analysis. Thisis a common modeling method used in the field of rock mechanicsand hydrogeology. LÄS MER

  3. 2. Fractured Rock Masses as Equivalent Continua - A Numerical Study

    Författare :Ki-Bok Min; KTH; []
    Nyckelord :fractured rock masses; equivalent continuum; discrete fracture Network DFN ; Distinct Element Method DEM ; Finite Element Method FEM ; Nuclear Waste Disposal; Coupled Thermo-Hydro-Mechanical Processes;

    Sammanfattning : In this thesis, fractured rock masses are treated asequivalent continua for large-scale analyses of rockengineering projects. Systematic developments are made for thedetermination of equivalent mechanical and hydraulic propertiesof fractured rock masses using a hybrid discrete fracturenetwork - distinct element method (DFN-DEM) approach. LÄS MER

  4. 3. Structural Uncertainties of Rock Fractures and their Effect on Flow and Tracer Transport

    Författare :Martin Stigsson; Vladimir Cvetkovic; Ki-Bok Min; KTH; []
    Nyckelord :Fracture; Flow; Transport; Orientation uncertainty; Roughness; Self-affine; Fractal; Shear; Aperture distribution.; Land and Water Resources Engineering; Mark- och vattenteknik;

    Sammanfattning : Att förstå flöde och transport av lösta ämnen genom sprickorna i berggrunden är viktigt för den långsiktiga säkerheten av ett geologiskt slutförvar av farligt avfall. I en diskret spricknätverksmodell byggs flödesvägarna upp av kedjor av flödesvägar genom de enskilda sprickorna i bergmassan. LÄS MER

  5. 4. Intratumoral heterogeneity in glioblastoma: subtype transition and cell-to-cell communication

    Författare :Min Guo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :glioblastoma; intratumoral heterogeneity; subtype transition; intercellular communication; U-343; SOX2; SFRP2; PROX1; THRAP3; TGFBI; NOTCH1; and ADAMTS1;

    Sammanfattning : Glioblastoma is a most aggressive brain tumor with a median overall survival of less than two years. The current treatment is surgery, chemotherapy, and radiotherapy. However, glioblastoma is difficult to treat and recurs some time after treatment. LÄS MER

  7. 5. Post-translational modifications of proteins in human breast cancer : proteomics studies of phosphorylation and nitration and implication of these PTMs in tumorigenesis

    Författare :Min Jia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer is the most common cancer in women. Even though improvements in diagnosis and treatment of breast cancer have been made, it is still the most common cause of cancer death in women. There is a great need to find biomarkers for early detection of the disease and novel drug targets to fight the cancer. LÄS MER